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. 2021 Nov 17;10(11):3206. doi: 10.3390/cells10113206

Figure 1.

Figure 1

Diverse organ system effects. FXR has functions in many organ systems throughout the body outside the GI–liver axis. In many systems FXR promotes positive effects while its effects in the CNS provide counter examples of potential FXR-induced damage (created with BioRender.com, accessed on 10 October 2021) [19,21,22,23,24,25,27,34,35,36,37,38,39,40].