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. 2021 Nov 11;22(22):12195. doi: 10.3390/ijms222212195

Figure 1.

Figure 1

Dependency of platelet activation by SW620 cells from the MACC1 expression. (A) Representative curves of platelet aggregation by light transmission measurement after contact with MACC1-positive SW620 Ctrl cells or the MACC1 KO variant. (B) ATP release from platelet dense granule induced by SW620 Ctrl and MACC1 KO cells. (C) Platelet adhesion to a cell layer of SW620 Ctrl or MACC1 KO cells exclude a diminished cell contact formation as the reason for lower platelet activation by the MACC1-positive cells. ** p < 0.01, *** p < 0.001.