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. 2021 Oct 28;7(11):916. doi: 10.3390/jof7110916
Therapeutic
(1–5.5 mg/L)
Subtherapeutic (<1 mg/L) Supratherapeutic (>5.5 mg/L) p-Value
Administration route, n (%)
Parenteral
Oral
29 (35.6)
16 (64.4)
7 (50.0)
7 (50.0)
22 (75.9)
7 (24.1)
0.235
Adverse effects, n (%) 0 (0.0) 0 (0.0) 4 (13.8) -
median dose/day (mg), (minimum–maximum) 400 (360–800) 480 (300–900) 560 (400–800) 0.113