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RIG-I deficiency exacerbates high-fat diet-induced obesity in mice. Wild-type (WT), RIG-I knockout (KO), or MDA5 KO mice were fed a normal chow diet (ND) or a high-fat diet (HFD) for 12 weeks. (A) Total body weight. (B) Body weight gain at 12-weeks. (C) Average food intake. The values represent the means ± SEM (n = 4–5). * p < 0.05.
