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. 2021 Nov 2;13(11):1836. doi: 10.3390/pharmaceutics13111836

Table 5.

The heats of fusion and the onset and peak temperatures of the melting of methylxanthines in the mixtures in HPMC.

Content of Caffeine in Mixture (%) Heat of Fusion (J/g)
ΔHf
Onset Temperature (°C)
Ton
Peak Temperature (°C)
Tp
10
30 3.7 220.6 233.5
50 20.5 235.3 239.2
70 34.2 235.9 238.3
90 82.5 235.5 237.3
100 103.5 236.9 237.9
Content of Theophylline in Mixture (%) Heat of Fusion (J/g)
Δ Hf
Onset Temperature (°C)
Ton
Peak Temperature (°C)
Tp
10
30 20.9 249.5 268.0
50 62.1 261.8 270.2
70 83.8 268.4 272.3
90 125.7 271.0 273.4
100 155.3 271.9 273.1