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. 2021 Nov 11;22(22):12206. doi: 10.3390/ijms222212206

Table 1.

Druggability scores calculated by DoGSiteScorer [38] of the pockets associated with clusters 1, 4, 5 and 6 for HePTP, PTPSL and STEP.

PTP Pocket (Site of Cluster) Druggability Probability Vol. Hull/Å3 % Polar Residues
HePTP C1/C2 0.83 617 39
HePTP C4 0.61 324 39
HePTP C5 0.81 522 29
HePTP C6 0.27 135 10
PTP-SL C1 0.61 428 45
PTP-SL C4 0.55 259 50
PTP-SL C5 0.74 604 29
PTP-SL C6 0.37 177 20
STEP C1 0.51 280 53
STEP C4 0.24 187 67
STEP C5 0.72 475 37
STEP C6 0.34 155 50
STEP C6′ 0.23 134 50