Table 1.
PTP | Pocket (Site of Cluster) | Druggability Probability | Vol. Hull/Å3 | % Polar Residues |
---|---|---|---|---|
HePTP | C1/C2 | 0.83 | 617 | 39 |
HePTP | C4 | 0.61 | 324 | 39 |
HePTP | C5 | 0.81 | 522 | 29 |
HePTP | C6 | 0.27 | 135 | 10 |
PTP-SL | C1 | 0.61 | 428 | 45 |
PTP-SL | C4 | 0.55 | 259 | 50 |
PTP-SL | C5 | 0.74 | 604 | 29 |
PTP-SL | C6 | 0.37 | 177 | 20 |
STEP | C1 | 0.51 | 280 | 53 |
STEP | C4 | 0.24 | 187 | 67 |
STEP | C5 | 0.72 | 475 | 37 |
STEP | C6 | 0.34 | 155 | 50 |
STEP | C6′ | 0.23 | 134 | 50 |