AMPAR	α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
ASD	Autism Spectrum Disorder;
AKT	protein kinase B;
BRAF	V-Raf murine sarcoma viral oncogene homolog B;
Camp	cyclic adenosine monophosphate;
CBL	Casitas B-lineage Lymphoma;
CFCS	Cardiofacio-Cutaneous syndrome;
CUL3	Cullin 3;
DEPDC5	DEP domain containing 5 protein;
EB	embryoid bodies;
eIF4E	eukaryotic translation initiation factor 4E;
EGFR	epidermal growth factor receptor;
ERK 1/2	extracellular signal-regulated kinase 1/2;
ESC	embryonic stem cells;
GABA	gamma-aminobutyric acid;
GAP	GTPase activating protein;
GATOR1	GAP activity towards Rags 1;
GEF	guanine nucleotide exchange factor;
HCN	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel;
ID	Intellectual Disability;
iPSC	induced pluripotent stem cells;
iNeurons	induced Neurons;
KO	knockout;
KRAS	kirsten rat sarcoma virus proto-oncogene, GTPase;
LAMTOR	also known as Ragulator, late endosomal/lysosomal adaptor and mitogen activated protein kinase and mechanistic target of rapamycin activator;
LTP	Long-term potentiation;
LTD	Long-term depression;
LZTR1	leucine zipper–like transcriptional regulator 1;
MAF	minor allele frequency;
MAP2K1/2 or MEK 1/2	mitogen activated protein kinase 1/2;
MEX3D	mex-3 RNA binding family member D;
MGLURs	metabotropic glutamate receptors;
MNK1/2	MAPK-interacting kinase;
MTORC1/2	mammalian target of rapamycin complex 1/2;
MWM	Morris water maze;
NCT	National Clinical Trial number
NF1	Neurofibromatosis type 1;
NMDA-R	N-methyl-D-aspartic acid receptor;
NPC	neural progenitor cell;
NPRL2	nitrogen permease regulator 2-like protein;
NRAS	neuroblastoma RAS viral oncogene homolog;
NS	Noonan Syndrome;
NSC	neural stem cell;
PI3K	Phosphoinositide 3-Kinase;
PTEN	Phosphatase and Tensin homolog;
RAF1	Raf-1 proto-oncogene, Serine/threonine kinase;
Rag A/B, C/D	Ras-related GTP-binding protein A/B, C/D;
Raptor	regulatory-associated protein of mTOR
RHEB	Ras homolog enriched in brain;
Rictor	rapamycin-insensitive companion of mTOR;
RIT1	Ras like without CAAX1;
RPSK	ribosomal protein S6 kinase;
RTK	receptor tyrosine kinases;
SHOC2	SHOC2 leucine rich repeat scaffold protein 2;
SMAD1	mothers against decapentaplegic homolog 1;
SPRED1	sprouty-related, EVH1 domain-containing protein 1
SYNGAP1	synaptic Ras GTPase Activating Protein 1;
SYNGAP1-ID	SYNGAP1-related intellectual disability;
S6K1	p70 S6 kinase 1;
TSC	Tuberous Sclerosis Complex;
4E-BP1	eukaryotic translation initiation factor 4E-binding protein.