. 2021 Oct 29;12(11):1738. doi: 10.3390/genes12111738

Table 3.

A summary of KEGG pathway analysis for differentially expressed genes.

Term	Genes	p-Value	FDR
Metabolic pathways	gls2a, gls2b, gpx9, gda, hacd1, chia.2, gyg1b, tecrl2b, zgc:153896, elovl4b, zgc:153704, cyp7a1, zgc:103586, pgam2, pde6g, lpin1, ATP8, aoc1, LOC559107, ndufa4l2a, zgc:109982, pts, tyr, si:ch211-214p16.3, gch2, ampd1, mdh1ab, ND4L, tecrl2a, dhrs3a, atpv0e2, agxta, chs1, cyp21a2, aldoab, gal3st1a, ckmt2b, th2, si:dkey-78a14.5, dpm3, spam1, csgalnact1b, nat8l, ptges, atp5ia, nme2a, ND1, ND3, ND5, gpx8, ND2, si:dkey-78a14.4, aanat2, ndufa1, adssl1, si:ch211-217a12.1, ATP6, entpd8, alpi.2, tymp, ndufa4, elovl8a, entpd5a, zgc:112320, pigw, haao, CYTB, ckma, cel.1, gstk4, hao2, nme2b.2, pigh, pfkma, hpda, pnp4b, ND4, aldh3b2, smyd1a, b3gnt5a, mocs1, uox, st3gal7, si:ch211-106j24.1, pde6c, ndufa2, ugt5e1, fhit, sdhdb, acot19, agxtb, cyp2r1, COX3, COX1, COX2, tyrp1b, pde6d, acp5a , sgpp2 , galnt6 , pik3c2g , gal3st1b , ugt5a1 , atic , glulc , sqlea , alp3 , aldh3b1 , p4ha1b , paics , elovl6l , ethe1 , plcd1a , zgc:100864 , zgc:154054 , ugt1a5 , cmasb , aldob , gstm.3 , cyp24a1 , ugt1a7 , cbr1l , zgc:123275 , fut9d , zgc:112332 , b4galnt3b , hao1 , ugt1a1 , mthfd1l , si:ch73-337l15.2 , ugt5a4 , ptgs2b , cmbl , mgst1.2 , rdh12l , dao.1 , zgc:163121 , nansb , si:ch211-276a23.5 , cox4i1l , pla2g4f.1 , ugt1a2 , ugt1a6 , cyp3a65 , cyp17a1 , alas2 , ptgs2a , bhmt , sqrdl , nqo1 , LOC565422 , ptgis , gstp1 , ugt2a4 , gstp2	1.14402 × 10⁻⁵³	1.61306 × 10⁻⁵¹
Calcium signaling pathway	slc25a4, adrb2b, atp2a1l, mylk4b, stim2a, mylk4a, camk1gb, fgf4, ednraa, casq1a, trdn, tnnc2, p2rx5, avpr1aa, p2rx8, si:rp71-17i16.4, cacna1sb, casq2, calm1b, egf, ednrba, zgc:56235, casq1b, orai1a, si:dkey-247m21.3, fgf1a, p2rx3a, ryr3, atp2a1, phkg1b, tacr3a , mcoln3a , plcd1a , p2rx1 , si:dkey-251i10.1 , cxcr4a , ltb4r2a , gna15.1 , gna14 *	2.39485 × 10⁻¹⁵	1.68837 × 10⁻¹³
Phototransduction	opn1mw2, gngt1, opn1mw1, guca1c, gnat1, guca1d, pde6g, rhol, gnat2, rho, guca1e, rcvrnb, rcvrn2, grk7a, rcvrn3, calm1b, zgc:112320, cnga1	6.05641 × 10⁻¹⁵	2.84651 × 10⁻¹³
Cardiac muscle contraction	atp2a1l, si:ch211-139a5.9, cacng6b, zgc:163073, zgc:86725, cacng1a, trdn, tnnt2d, atp1b1a, tpm4b, tnnt2e, cacna1sb, casq2, atp1b2b, CYTB, atp1a3b, atp1b4, smyhc1, atp2a1, atp1b2a, COX3, COX1, COX2, cox4i1l , atp1a1a.2	2.86244 × 10⁻¹⁴	1.00901 × 10⁻¹²
Drug metabolism—other enzymes	zgc:103586, si:dkey-78a14.5, nme2a, si:dkey-78a14.4, gstk4, nme2b.2, aldh3b2, ugt5e1, ugt5a1 , tpmt.1 , tpmt.2 , aldh3b1 , ugt1a5 , gstm.3 , ugt1a7 , ugt1a1 , ugt5a4 , mgst1.2 , ugt1a2 , ugt1a6 , gstp1 , ugt2a4 , gstp2 *	4.12652 × 10⁻¹³	1.16368 × 10⁻¹¹
Cell adhesion molecules	cldn7a, cldn19, mpz, cldn5b, mag, si:ch211-286o17.1, cldnj, cdh15, itgb1a, cd99l2, cldnf, cdh1, cldnc, cldn8, itgb1b.1, oclnb, zgc:110333, cldn7b, cldnb, oclna, cldn1, cldne, si:ch211-95j8.5, cldni, zgc:136892	2.61473 × 10⁻¹²	6.14462 × 10⁻¹¹
Aminoacyl-tRNA biosynthesis	trnS2, trnA, trnH, trnD, trnE, trnG, trnK, trnN, trnM, trnY, trnP, trnQ, trnC, trnR, trnI, trnL1, trnS1	4.82031 × 10⁻¹²	9.70947 × 10⁻¹¹
Biosynthesis of cofactors	pts, gch2, dhrs3a, nme2a, adssl1, alpi.2, haao, nme2b.2, hpda, mocs1, ugt5e1, ugt5a1, alp3, ugt1a5, ugt1a7, zgc:112332, ugt1a1, mthfd1l, ugt5a4, rdh12l, ugt1a2, ugt1a6, alas2, nqo1, ugt2a4	2.2858 × 10⁻¹¹	3.55548 × 10⁻¹⁰
Metabolism of xenobiotics by cytochrome P450	gstk4, aldh3b2, ugt5e1, ugt5a1,aldh3b1, ugt1a5, gstm.3, ugt1a7, cbr1l, ugt1a1, ugt5a4, mgst1.2, ugt1a2, ugt1a6, gstp1, ugt2a4, gstp2	2.50462 × 10⁻¹¹	3.55548 × 10⁻¹⁰
Regulation of actin cytoskeleton	cfl2, cxcl12b, mylk4b, mylk4a, fgf4, mylpfb, cxcl12a, LOC101885790, si:dkey-44g17.6, itga10, egf, tmsb, scinla, pfn2l, itgb1a, fgf1a, si:ch73-116o1.2, brk1, itga2.2, itgb1b.1, cxcr4a, rac2, zgc:86896, myh9a, fn1b, itgb3a, gsnb, pfn1, cfl1l, zgc:101810	2.52162 ×10⁻¹¹	3.55548 ×10⁻¹⁰

*: upregulated, normal text: downregulated, FDR: false discovery rate.