Table 2.
Performance evaluation of each Lasso regression model.
| Cognitive Domain | N | Balanced Accuracy (%) |
Sensitivity (%, 95% CI) |
Specificity (%, 95% CI) |
PPV (%, 95% CI) |
NPV (%, 95% CI) |
|---|---|---|---|---|---|---|
| Global cognition | 212 | 71 | 70 (59–80) | 71 (63–79) | 58 (47–68) | 81 (72–87) |
| Verbal memory | 212 | 79 | 76 (63–86) | 82 (76–88) | 62 (50–73) | 90 (84–94) |
| Visual memory | 212 | 62 | 71 (56–82) | 54 (46–62) | 33 (24–42) | 85 (77–91) |
| Attention-IPS | 212 | 73 | 71 (54–85) | 75 (68–81) | 38 (27–50) | 92 (86–96) |
| Semantic fluency | 210 | 62 | 51 (44–59) | 73 (57–86) | 89 (81–94) | 29 (19–36) |
Balanced Accuracy is defined as the arithmetic mean of sensitivity and specificity. Sensitivity is defined as the proportion of subjects who developed cognitive impairment that are correctly classified. Specificity is defined as the proportion of subjects who did not develop cognitive impairment that are correctly classified. The predictive model of cognitive impairment in semantic fluency was generated with 210 patients. CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; IPS: information processing speed.