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. 2021 Oct 21;13(11):1759. doi: 10.3390/pharmaceutics13111759

Figure 7.

Figure 7

Ribbon representation of RdRp of SARS-CoV-2 (PDB code: 6yyt) which shows the active site of the enzyme (a) and illustrates the various domains of the enzyme (b). The RdRp structure consists of three subunits (nsp12, nsp8, and nsp7). The RdRp domain is fashioned into three subdomains (palm, fingers, and thumb subdomains). The nsp12 is mainly forms the active site of RdRb and comprised three domains (INRAN domain, C-terminal domain, and interface domain). The nsp8 and nsp7 subunits are binding to the fingers and thumb subdomains.