FIG. 3.

Sequence similarity between Bur2 and cyclins. (A) Alignment of the cyclin box region of Bur2 with those of Spx63 of C. albicans, Pch1 of S. pombe (accession no. U92879) and cyclin T of Mus musculus (accession no. AF113951). Residues identical in all four sequences are shown in black. Residues identical or similar in three of four sequences are boxed. Asterisks mark residues that are nearly invariant in cyclins (25). Alignment was constructed using the Clustal method in MegAlign. (B) Localization of Bur2 on a phylogenetic tree of cyclins. Alignment of cyclin box regions was used to create a phylogenetic tree containing Bur2 and other cyclins.