Table 4.
Coagulation parameters according to the Charlson Comorbidity Index in IE patients.
| CI | 0–1 (n = 22) | 2–3 (n = 34) | ≥4 (n = 142) | p-Value ^ |
|---|---|---|---|---|
| D-dimers, ng/mL | 452 (215–866) | 649 (337–1037) | 614 (259–1222) | 0.439 |
| Fibrinogen, mg/dL | 439 (383–605) | 423 (355–580) | 409 (306–537) | 0.323 |
| PT-INR | 1.35 (1.25–1.58) | 1.20 (1.09–1.37) | 1.33 (1.20–2.14) | 0.006 |
| aPTT, seconds | 33.2 (29.3–38.2) | 30.9 (29–34) | 33 (30.1–38.4) | 0.057 |
| Platelet count, cells103/μL | 209 (149–302.7) | 229 (183–280) | 201 (139–259) | 0.089 |
| Homocysteine, mcmol/L | 14 (11–16.2) | 12 (11–18) | 15 (12–21) | 0.060 |
Data are median (IQR). ^ Kruskal–Wallis test. Abbreviations: aPTT: activated partial thromboplastin time; PT-INR: prothrombin time international normalized ratio; CCI: Charlson Comorbidity Index; IE: infective endocarditis. Statistically significant results are marked in bold.