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Inhibitory activity of Peters’ elephant-nose fish oil, and its isolates against both COX-1 and COX-2 calculated as IC50 (µM) ± SEM (n = 3).
| Compound | COX-2 (µM) | COX-1 (µM) | COX-2/COX-1 |
|---|---|---|---|
| 1 | >100 | >100 | - |
| 2 | >100 | >100 | - |
| 3 | >100 | >100 | - |
| 4 | 2.41 ± 0.2 * | 18.5 ± 0.4 * | 0.13 |
| 5 | >100 | >100 | - |
| 6 | >100 | >100 | - |
| Crude oil | 15.27 ± 0.3 * | 46.33 ± 0.2 * | 0.33 |
| Celecoxib ® | 0.125 ± 0.2 * | 2.53 ± 0.3 * | 0.05 |
* Statistically significant at p < 0.05.
