Table 3.
Odds ratios and 95% confidence intervals for the possible prognostic factors of AKI development.
| Variables | Univariate Model | Multivariate Model | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Age (years) | 1.011 | 0.998–1.025 | 0.10 | 1.007 | 0.989–1.026 | 0.434 |
| Sex | ||||||
| Male | Ref. value | Ref. value | ||||
| Female | 1.280 | 0.728–2.250 | 0.40 | 2.235 | 0.999–4.998 | 0.050 |
| SOFA score | 1.116 | 1.003–1.242 | 0.04 * | 0.878 | 0.750–1.028 | 0.106 |
| NGAL (ng/mL) | 1.006 | 1.004–1.009 | <0.0001 * | 1.005 | 1.002–1.008 | 0.0001 * |
| LoS in the ICU (days) | 1.116 | 1.085–1.148 | <0.0001 * | 1.112 | 1.078–1.148 | <0.0001 * |
* p < 0.05. A univariate logistic regression model was used to evaluate the association of NGAL and other factors with the development of AKI. Afterwards, a multivariate logistic regression model was used to evaluate the association of NGAL with AKI development in the presence of potential confounders, namely, age, sex, SOFA score, and length of stay in the ICU. Definitions of abbreviations: AKI = Acute kidney injury; ICU = Intensive care unit; LoS = Length of stay; NGAL = Neutrophil gelatinase-associated lipocalin; SOFA = Sequential organ failure assessment.