Table 3.

Regulatory approaches.

Regulatory Agency	Proposal	Reference
EPA	Propose using Problem Formulation- Risk assessment	[102]
European Food Safety Authority (EFSA)	Do not directly address the spray products, but a literature review focused on RNAi-based GM plants and Risk Assessment	[86]
OECD	Proposed using risk assessment to evaluate the toxicity profile and exposure by using the current regulatory framework for small-molecule agrochemicals as a general framework for dsRNA-based agricultural products. Proposed using the experience with the review of dsRNA-based GE crops	[11]