Figure 8.

Menaquinone biosynthesis genes are increased in cirrhotic patients. Humann3 analysis of fecal metagenomic dataset of patients with healthy (H, red, n = 52), compensated (C, green, n = 48), or decompensated (D, blue, n = 44) liver cirrhosis diagnosis for EC numbers in menaquinone biosynthesis. Individual box plots are labeled with the EC number matching the enzymatic step in pathway schematic. Significance is denoted with a red asterisk (*; adjusted p-values < 0.05) with the healthy group as reference.