Table 6.

Difference in reporting of systemic adverse reactions in the 7 days after the first and second vaccine dose administration.

	Dose 1	Dose 2	Sig.
Fever	5.5% (95%CI 2.8–9.6)	32.0% (95%CI 25.6–38.9)	0.000
Fatigue	41.5% (95%CI 34.6–48.7)	74.5% (95%CI 67.9–80.4)	0.000
Chills	12.0% (95%CI 7.8–17.3)	40.0% (95%CI 33.2–47.1)	0.000
Headache	34.5% (95%CI 27.9–41.5)	55.5% (95%CI 48.3–62.5)	0.000
Muscle/joint pain	25.5% (95%CI 19.6–32.1)	56.0% (95%CI 48.8–63.0)	0.000
Gastrointestinal symptoms	6.0% (95%CI 3.1–10.2)	15.0% (95%CI 10.4–20.7)	0.003
Lymph node enlargement	10.5% (95%CI 6.6–15.6)	18.5% (95%CI 13.4–24.6)	0.015