Table 3.
Variants detected among feline herpesvirus type 1 (FHV-1) strains isolated from 10 captive cheetahs, a reference FHV-1 strain (C-27), and the viral strain in the Merial modified live vaccine (MLV). Note the infrequent detection of unique synonymous (0) and non-synonymous variants (5) between the MLV strain and isolates from vaccinated cheetahs. Variants were identified using Geneious Prime ver 2020.2.4.
| Gene | Number of Unique Variants (FHV-1 All Cheetah Isolates Compared with C-27) | Number of Unique Variants (MLV Strain Compared with Isolates from Vaccinated Cheetahs (MM-2, -3, -7, and -9)) | ||
|---|---|---|---|---|
| Synonymous Variants | Non-Synonymous Variants | Synonymous Variants | Non-Synonymous Variants | |
| ICP4 | 4 | 6 | 0 | 0 |
| UL10 | 0 | 1 | 0 | 0 |
| UL12 | 2 | 0 | 0 | 0 |
| UL16 | 0 | 2 | 0 | 0 |
| UL17 | 0 | 1 | 0 | 0 |
| UL19 | 1 | 0 | 0 | 0 |
| UL20 | 2 | 0 | 0 | 0 |
| UL25 | 1 | 2 | 0 | 0 |
| UL28 | 2 | 1 | 0 | 0 |
| UL29 | 0 | 1 | 0 | 0 |
| UL32 | 1 | 0 | 0 | 0 |
| UL36 | 3 | 0 | 0 | 0 |
| UL38 | 0 | 2 | 0 | 0 |
| UL4 | 1 | 0 | 0 | 0 |
| UL40 | 1 | 1 | 0 | 0 |
| UL41 | 2 | 3 | 0 | 1 |
| UL43 | 1 | 0 | 0 | 0 |
| UL44 | 0 | 1 | 0 | 0 |
| UL47 | 1 | 0 | 0 | 0 |
| UL48 | 0 | 1 | 0 | 4 |
| UL50 | 0 | 1 | 0 | 0 |
| UL52 | 0 | 1 | 0 | 0 |
| UL53 | 1 | 0 | 0 | 0 |
| UL54 | 1 | 1 | 0 | 0 |
| UL55 | 0 | 1 | 0 | 0 |
| UL7 | 0 | 1 | 0 | 0 |
| UL9 | 1 | 0 | 0 | 0 |
| US2 | 1 | 0 | 0 | 0 |
| US4 | 1 | 0 | 0 | 0 |
| US7 | 0 | 1 | 0 | 0 |
| US9 | 0 | 1 | 0 | 0 |
| UL3.5 | 1 | 1 | 0 | 0 |
| UL35 | 0 | 1 | 0 | 0 |
| UL5 | 0 | 1 | 0 | 0 |
| UL6 | 0 | 1 | 0 | 0 |