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. 2021 Nov 9;13(11):2251. doi: 10.3390/v13112251

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Clinical and virological findings in hamsters intranasally challenged with 16 and 27,000 pfu SARS-CoV-2. (a) Weight loss compared to the day of challenge. (b) Clinical score. (c) Viral RNA levels in throat swabs. (d) Quantification of live virus in throat swabs. Data show mean values with error bars denoting standard error from n = 6 hamsters per group. *, p < 0.05 (Mann-Whitney test); NT, not tested as samples not collected at these timepoints; and <, below the assay detection limits.