Table 2.
Laboratory data of study animals.
| Control (n = 10) |
FR (n = 10) |
FR+Dapa (n = 10) |
FR+Mg (n = 10) |
|
|---|---|---|---|---|
| Body weight (g) | 586.6 ± 56.5 | 597.4 ± 57.2 | 521.6 ± 21.6 *,# | 615.1 ±72.0 |
| Blood pressure (mmHg) | 149.4 ± 2.6 | 155.6 ± 7.7 | 145.5 ± 6.9 # | 155.7 ±6.2 |
| Water intake (mL/day) | 52.2 ± 11.0 | 42.5 ± 7.6 | 52.0 ± 3.6 | 40.1 ±12.4 |
| 24h Urine (mL/day) | 29.4 ± 10.9 # | 20.0 ± 8.4 * | 41.7 ± 12.7 *,# | 17.9 ±7.6 * |
| Blood Glucose (mg/dL) | 109.0 ± 14.3 | 134.6 ± 22.4 * | 99.6 ± 12.5 # | 109.1 ± 10.2 # |
| Blood Triglyceride (mg/dL) | 70.7 ± 27.1 | 231.0 ± 137.9 * | 131.0 ± 62.8 # | 192.1 ± 59.8 * |
| Blood Insulin (μU/mL) | 3.0 ± 2.2 | 11.6 ± 9.2 * | 4.2 ± 1.4 # | 7.3 ± 2.7 *,# |
| HOMA-IR | 0.8 ± 0.6 | 3.9 ± 3.1 * | 1.0 ± 0.3# | 1.6 ± 0.6# |
| Blood Creatinine (mg/dL) | 0.29 ± 0.05 | 0.26 ± 0.05 | 0.27 ± 0.04 | 0.30 ± 0.06 |
| Blood Calcium (mg/dL) | 9.1 ± 0.7 | 9.2 ± 0.7 | 9.2 ± 0.4 | 9.9 ± 0.5 |
| Blood Mg (mg/dL) | 2.4 ± 0.3 | 1.8 ± 0.2 * | 2.1 ± 0.4 *,# | 2.2 ± 0.2# |
| Blood i-PTH (pg/mL) | 326.6 ± 104.1 | 149.9 ± 32.6 * | 175.2 ± 50.0 * | 181.9 ± 63.8 * |
| Blood 1,25-dihydroxyvitamin-D3 (pg/mL) | 71.0 ± 19.8 | 53.6 ± 11.6 * | 54.2 ± 20.5 * | 56.8 ± 8.9 * |
| FEMg(%) Urine Mg (mg/24 h) |
4.1 ± 2.9 19.6 ± 7.3 |
2.7 ± 1.4 * 10.1 ± 4.9 * |
1.9 ± 1.3 *,# 5.3 ± 3.6 *,# |
6.7 ± 1.8 *,# 19.6 ± 4.4 # |
FEMg: fractional excretion of magnesium; * p < 0.05 vs. control group; # p < 0.05 vs. FR group.