Table 2.
The KEGG enrichment results of differentially methylated genes related to aging (based on SIMPO algorithm).
| Category | Term | p-Value | Related Genes |
|---|---|---|---|
| KEGG_PATHWAY | Signaling pathways regulating pluripotency of stem cells | 1.53 × 10−3 |
POU5F1
WNT16 AKT2 RIF1 ID1 |
| KEGG_PATHWAY | Cellular senescence | 2.69 × 10−3 |
AKT2
RRAS2 CCDC109A SIRT1 RBBP4 |
| KEGG_DISEASE | Parkinsonian syndrome | 1.74 × 10−3 |
PINK1
DNAJC13 |
| KEGG_DISEASE | Lissencephaly | 2.44 × 10−3 |
NDE1
TMTC3 |
| KEGG_DISEASE | Maturity onset diabetes of the young (MODY) | 3.26 × 10−3 |
HNF1B
PDX1 |