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A multiplex family of schizophrenia with the R1087Q mutation of the BSN gene. (A) The pedigree shows the dominant inheritance of schizophrenia in this family. Only five members of this family were available for study. (B) Chromatograms show the wild-type G homozygote at the nucleotide position 49690249 of the BSN gene in the unaffected mother. At the same time, the other four patients carried the G-to-A heterozygous mutation of the BSN gene.
