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. 2021 Oct 28;13(11):762. doi: 10.3390/toxins13110762

Table 3.

Estimate of probable daily intakes of Alternaria mycotoxins based on urinary concentrations.

Mycotoxins Excretion Rate PDI (ng/kg bw/day) TTC (ng/kg bw/day) Exceeding
TTC (%)
ER (%) Reference Min Mean Median P95 Max
AOH 8.3 Puntscher et al. [36] a 3.28 419 6.57 1880 11,400 2.5 100
2.8 Puntscher et al. [37] a 9.74 1240 19.5 5580 33,700 100
AME 6.7 Puntscher et al. [36] a 2.33 36.8 4.76 105 339 2.5 99.2
2.6 Puntscher et al. [37] a 6.01 94.8 12.3 272 873 100
TeA 89 Asam et al. [24] b 0.468 52.1 1.75 284 1940 1500 0.372
TEN 0.9 Puntscher et al. [37] a 15.2 107 27.8 442 2760 1500 1.12

AOH = alternariol; AME = alternariol monomethyl ether; TeA = tenuazonic acid; TEN = tentoxin; ER = excretion rate; nPDI = probable daily intake; TTC = threshold of toxicological concern. a Studies performed in rats. b Study including two volunteers.