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. 2021 Nov 22;22(22):12559. doi: 10.3390/ijms222212559

Figure 5.

Figure 5

Percentage of Cal 27 apoptotic cells as determined by caspase 3/7-positivity. After Cal 27 cells were stimulated with LPS + LTA for 72 h, Cal 27 cells were treated with ML218 HCl and capsaicin [3] for 24 h in the absence or presence of oral bacterial antigens. LPS (5 µg/mL), LL = combined LPS (5 µg/mL) + LTA (5 µg/mL), M = ML218 HCl, C = capsaicin [3]. Letter before the arrow represents pre-stimulation, e.g., LPS -> M is LPS pre-stimulation and then treatment with ML218 HCl. * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001 are statistically significant. n = nine biological replicates. Error bars represent standard error of the mean.