Table 1.
Summary of data sets used to evaluate the IV-MBM EQP v2.0 model.
| Data Set | Number, Type of Chemicals, Range of log KOW,N and log KAW,N | Cell Type and Assay Conditions | Exposure Period (h) |
|---|---|---|---|
| Tanneberger et al. [38] |
n = 27 Neutral (25) & IOC (2) log KOW,N = −4.15–7.54 log KAW,N = −10.5–0.31 |
Fish RTgill-W1 24 well plate 19 °C FBS = 0% |
24 |
| Dupraz et al. [39] |
n = 13 Neutral organics log KOW,N = −3.20–5.50 log KAW,N = −13.3–−3.92 |
Algae 48 well plate 20 °C FBS = 0% |
96 |
| Huchthausen et al. [40] |
n = 12 Neutral (1) and IOCs (11) log KOW,N = −0.07–3.97 log KAW,N = −17.6–−5.21 |
Human MCF7 and HEK293H 96 well plate 37 °C FBS = 10% (AREc32) FBS = 2% (PPARγ) |
24 |
| Schug et al. [41] |
n = 16 Neutral organics log KOW,N = 1.83–6.25 log KAW,N = −5.19–−0.69 |
Fish RTgutGC 24 well plate 19 °C FBS = 0% |
24 |
Chemicals are classified as IOCs if an ionizable functional group is present.