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. 2021 Nov 27;24(12):103523. doi: 10.1016/j.isci.2021.103523

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Full model (57 markers) performance versus parsimonious model (10 markers) performance for various time to event durations

(A and C) show the ROC for time to mortality at 3, 7, 15, 22, and 30 days from admission for 57 markers and 10 markers model respectively.

(B and D) show the progression of area under ROC for predicting severity score of 4 at 5-day intervals for 57 markers and 10 markers model respectively. Shaded regions identify the 95% confidence interval.

(E and F) show UMAP visualization of time to mortality (in days) of patients with severity 4 on the deep profiler latent space (with local neighborhood of 250) for first model in the ensemble.