Table 2.
24 hours | 48 hours | |||||
---|---|---|---|---|---|---|
Placebo group | MEL group | p value | Placebo group | MEL group | p value | |
Mean ± SD [median (25°-75°)] | Mean ± SD [median (25°-75°)] | |||||
Melatonin (pg/mL) | 28.57 ± 46.24 [10 (1-43)] | 52759.30 ± 63529.09 [18309 (8886-100831)] |
<0.001∗ | 38.50 ± 44.01 [17 (4-121)] | 279397.6 ± 516344.2 [37349 (10108-274844)] | <0.001∗ |
NPBI (micromol/L) | 2.40 ± 3.46 [0.7 (0.2-3.3)] | 3.97 ± 3.13 [4 (1-6)] | 0.113 | 2.99 ± 3.56 [0.8 (0.1-6)] | 2.23 ± 2.37 [1 (0.6-5)] | 0.525 |
AOPP (micromol/dL) | 44.66 ± 26.54 [36 (28-45)] | 36.07 ± 16.03 [32 (24-42)] | 0.297 | 54.96 ± 24.33 [53 (33-75)] | 51.66 ± 18.11 [47 (38-60)] | 0.715 |
F2-Isoprostanes (pg/mL) | 82.47 ± 51.30 [80 (31-121)] | 75.05 ± 87.75 [46 (20-93)] | 0.168 | 89.97 ± 52.01 [80 (62-127)] | 36.48 ± 33.85 [24 (10-68)] | <0.008∗ |
Data are expressed as mean ± SD and median (25-75°C).