Table 4.
Comparison of predictive efficacy among different liver function-related indices.
| Training cohort | Validation cohort | |||||||
|---|---|---|---|---|---|---|---|---|
| C-index | AUC (95% CI) | LAT χ2 | C-index | AUC (95% CI) | LAT χ2 | |||
| 3-year OS | 5-year OS | 3-year OS | 5-year OS | |||||
| AGR | 0.64 (0.49-0.78) | 0.63 (0.48-0.76) | 0.65 (0.52-0.78) | 11.2 | 0.62 (0.50-0.74) | 0.59 (0.50-0.69) | 0.63 (0.52-0.73) | 6.7 |
| ALBI grade | 0.61 (0.48-0.76) | 0.61 (0.46-0.76) | 0.63 (0.50-0.77) | 4.9 | 0.52 (0.42-0.64) | 0.51 (0.41-0.61) | 0.53 (0.43-0.64) | 3.1 |
| CP grade | 0.52 (0.37-0.68) | 0.52 (0.36-0.67) | 0.53 (0.38-0.68) | 2.2 | 0.50 (0.38-0.62) | 0.49 (0.38-0.57) | 0.52 (0.40-0.63) | 0.7 |
Abbreviations: AUC: area under the curve; LAT χ2; likelihood ratio test χ2; OS: overall survival; AGR: albumin to gamma-glutamyltransferase ratio; ALBI grade: albumin-bilirubin grade; CP grade: Child-Pugh grade. ∗Statistically significant.