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. 2021 May 24;51(1):43–58. doi: 10.1007/s00256-021-03799-4

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© The Author(s) 2021

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Fig. 6 — MRI illustration of a diffuse medullary infiltration pattern in myeloma using T1w (a) and STIR (b) sequences. It is characterized by decreased signal intensity of the bone marrow on T1w sequences (a) and a correspondingly increased signal on STIR (b) sequences. On T1w images (a), the signal intensity of the bone marrow is equal to the intervertebral disc and the muscle, which is known as the “bright disc” sign