Table 2.

Number of genes, spontaneous base substitution rate, EMS treated mutation rate and estimated number of function affecting variants for different model organisms.

Specie	Number of genes	Spontaneous per base per generation mutation rate	EMS treated per gene per generation mutation rate	Estimated number of function affecting variants produced
C. elegans	a19,404	e 2.5 × 10−9	l2.5 × 10−3	49
D. melanogaster	b13,601	f3.5 × 10−9; g5.49 × 10−9	m1.0 × 10−3	14
A. thaliana	c27,655	h6.95 × 10−9, i5.90 × 10−9	i3.0 × 10−3	83
D. pulex (OP)	d18,440	j2.30 × 10−9, k7.17 × 10−9	4.1 × 10−3	76
D. pulex (CP)	d18,440	k4.53 × 10−9	3.2 × 10−3	59
D. pulicaria	27,846	–	4.4 × 10−3	123

Daphnia estimates are based on the results from 25 mM EMS treatment.

^aChen et al. (2005).

^bAdams et al. (2000).

^cCheng et al. (2017).

^dYe et al. (2017).

^eDenver et al. (2009).

^fKeightley et al. (2009).

^gSchrider et al. (2013).

^hWeng et al. (2019).

ⁱOssowski et al. (2010).

^jFlynn et al. (2017).

^kKeith et al. (2016).

^lGengyo-Ando and Mitani (2000).

^mSpradling (1997).