Table 1.
Demographic and clinical characteristics of children by cluster.
| Characteristic | Cluster | |||
|---|---|---|---|---|
| 1 | 2 | 3 | p-value | |
| n = 27 (36%) | n = 11 (15%) | n = 36 (49%) | ||
| Age (years), | 1.06 | 1.67 | 0.58 | 0.0739 |
| Median (IQR) | (0.4, 2.5)) | (0.78, 2.8) | (0.12, 1.7) | |
| Sex, n (%) | ||||
| Female | 12 (44%) | 2 (18%) | 16 (44%) | 0.2619 |
| Male | 15 (56%) | 9 (82%) | 20 (56%) | |
| Race, n (%) | ||||
| Black | 15 (56%) | 8 (73%) | 15 (42%) | 0.4985 |
| White | 9 (33%) | 3 (27%) | 16 (44%) | |
| Unknown | 0 (0%) | 0 (0%) | 3 (8%) | |
| Multiple | 3 (11%) | 0 (0%) | 2 (6%) | |
| Ethnicity, n (%) | ||||
| Hispanic or Latino | 1 (4%) | 0 (0%) | 2 (6%) | 0.7111 |
| Non-Hispanic or Latino | 26 (96%) | 11 (100%) | 34 (94%) | |
| Severity of Illness Scores, median (range) | ||||
| PRISM III | 15 (9, 16) | 23 (12, 26) | 12.5 (8, 18) | 0.0125 |
| PELOD | 6 (5, 7) | 7 (4, 11) | 6 (4, 8) | 0.4333 |
| PARDS severity | ||||
| Low (No/Mild) | 13 (48%) | 7 (64%) | 30 (83%) | 0.0122 |
| High (Moderate/Severe) | 14 (52%) | 4 (36%) | 6 (17%) | |
| Ventilator Days, median (Q1-Q3) | 7 (3, 11) | 7 (6, 19) | 3.5 (2, 6) | 0.0024 |
| 28 day Ventilator-free Days, median (Q1-Q3) | 21 (16, 25) | 21 (9, 22) | 24.5 (22, 26) | 0.0026 |
| Extracorporeal Life Support, n (%) | 3 (11%) | 2 (18%) | 2 (5.6%) | 0.4462 |
| Length of Stay, median (IQR) | ||||
| PICU (days) | 8 (5, 14) | 10 (9, 21) | 6.5 (3.25, 10) | 0.0269 |
| Hospital (days) | 11 (8, 22) | 16 (10, 22) | 11 (7, 16.25) | 0.3668 |
| 28-day Mortality, n (%) | ||||
| Dead | 2 (7.4%) | 1 (9.1%) | 0 (0)% | 0.1256 |
| Respiratory Culture, n (%) | ||||
| No Growth | 2 (7.4%) | 1 (9.1%) | 9 (25%) | 0.4169 |
| Viral Only | 7 (26%) | 4 (36.4%) | 5 (14%) | |
| Bacterial Growth only | 3 (11%) | 1 (9%) | 3 (8%) | |
| Virus + Bacterial Co-detection | 15 (55%) | 5 (45%) | 19 (53%) | |