Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 26;11:22982. doi: 10.1038/s41598-021-02371-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Autophagic and endocytic compartments depicted by transmission electron microscopy. (A) Schematic depiction of the autophagic and endocytic pathways used by the cells for the degradation and recycling of material. (B–E) TEM images of control (B), TBI (C), PF (D) and TBI + PF (E) cells. Autophagic and endocytic vacuoles at various stages of maturation are denoted. (F) The number of autophagic vacuoles (AVi and AVd) per TEM image was quantified; analyzing a total of 55–68 TEM images of five cells per experimental group. Statistical analysis was conducted using the Kruskal–Wallis test followed by Dunn’s multiple comparisons test, *p ≤ 0.05 **p ≤ 0.01 ***p ≤ 0.001. Potential fusion events are marked by stars (*). Abbreviations used: AVd degradative autophagic vacuole/autophagic compartment, AVi immature autophagic vacuole/autophagosome, EE early endosome, LE late endosome, Ly Lysosome, MVB multivesicular body, N nucleus, P phagophore/isolation membrane.