Anak #1 (2020)106
|
15 |
M |
NA |
Yes |
Oral cavity (retromolar trigone) |
T3N1M0 |
42.5 Gy total (in 25 fractions) |
Mucositis, wound site breakdown, cerebral edema, somnolence |
Yes (terminated) |
DOD (6 mo pD) |
- |
- |
Beckham #6 (2019)65
|
29 |
F |
C |
Yes |
Oral cavity (tongue) |
T2N1 |
66 Gy total to oral cavity (in 33 fractions), 50.4 Gy total to bilateral neck |
Mucositis (grade 2), dermatitis (grade 2) |
No |
DOD (13 mo pD, 12 mo pS, 9 mo pRT) |
Yes |
- |
Nolan 2017100
|
31 |
M |
NA |
Yes (12) |
Oral cavity (buccal mucosa) |
NA |
Dose NA |
NA |
No |
DOD (9 yr pD) |
Yes* [Table 7] |
- |
Kutler #10 (2016)4
|
48.5 |
M |
J |
No |
Oral cavity (retromolar trigone) |
T4N2bM0 |
40 Gy total (200 cGy x20 fractions) over 33 days |
Mucositis (high grade), dysphagia, cytopenia, sepsis |
Yes |
DOD (10 mo pS) |
- |
- |
Kutler #1 (2016)4
|
30.2 |
F |
A |
No |
Oral cavity (buccal gingiva) |
T4N0M0 |
25 Gy total |
Sepsis |
Yes |
DOD (16 mo pS) |
Yes |
- |
Kutler #18 (2016)4
|
43.9 |
M |
A |
No |
Oral cavity (alveolus) |
T4N2bM0 |
61 Gy total over 55 days |
Mucositis (high grade), cytopenia, graft site breakdown, mandibular hardware removal |
No |
DOD (172 mo pS) |
Yes |
- |
Kutler #17 (2016)4
|
36.9 |
F |
A |
No |
Oral cavity (alveolus) |
T4N1M0 |
56 Gy total |
Mucositis (high grade), dysphagia, cytopenia, hemorrhage, pleural thickening, sepsis |
No |
DOD (171 mo pS) |
- |
- |
Kutler #20 (2016)4
|
26.8 |
F |
C |
Yes |
Oral cavity (submandibular) |
T4N2cM0 |
Dose NA |
Dysphagia, dyspnea, cardiac arrest |
Yes |
DOD (20 mo pS) |
- |
- |
Kutler #12 (2016)4
|
42.1 |
F |
A |
No |
Oral cavity (alveolus) |
T4N2bM0 |
64.6 Gy total (170 cGy x30 fractions) over 70 days |
Dysphagia, cytopenia |
No |
DOD (113 pS) |
- |
- |
Kutler #30 (2016)4
|
41.1 |
F |
A |
No |
NA |
TXN2bM0 |
60 Gy total (200 cGy x30 fractions) over 39 days |
Mucositis (high grade), dysphagia, cytopenia, hemorrhage, trismus, xerostomia, fibrosis, esophageal stenosis |
No |
NED (178 mo pS) |
- |
- |
Kutler #9 (2016)4
|
20.9 |
M |
P |
No |
Oral cavity (tongue) |
T4N2cM0 |
70.2 Gy total (180 cGy x39 fractions) over 50 days |
Mucositis (high grade), dermatitis, cytopenia, sepsis |
No |
DOD (34 mo pS) |
- |
- |
Kutler #2 (2016)4
|
42.1 |
M |
A |
Yes |
Larynx (supraglottis) |
T2N2bM0 |
55.8 Gy total (180 cGy x22 fractions) over 31 days |
Mucositis (high grade), dysphagia, laryngeal edema, fibrosis, esophageal stenosis |
No |
DOD (341 mo pS) |
Yes |
- |
Kutler #33 (2016)4
|
29 |
F |
C |
Yes |
Oral cavity (tongue) |
T2N1M0 |
50 Gy total (200 cGy x25 fractions) over 31 days |
Trismus, erythema |
No |
DOD (31 mo pS) |
- |
- |
Kutler #34 (2016)4
|
44 |
F |
A |
No |
Oral cavity (tongue) |
T1N0M0 |
25 Gy total |
Erythema |
No |
DOD (73 mo pS) |
- |
- |
Bonfim #4 (2016)84
|
24 |
M |
NA |
Yes |
Oral cavity |
T4aN2M0 |
Dose NA |
NA |
NA |
AWD (NA) |
- |
- |
Bonfim #8 (2016)84
|
12 |
F |
NA |
Yes |
Oral cavity |
T2N0M0 |
Dose NA |
NA |
NA |
DOD (NA) |
- |
- |
Kaplan 201187
|
43 |
F |
NA |
NA |
Oral cavity (floor of mouth) |
NA |
Dose NA |
NA |
No |
NED (19 mo pS) |
- |
Pharynx |
Chao 2010117
|
43 |
F |
NA |
NA |
Oral cavity (floor of mouth, mandible) |
NA |
Dose NA |
NA |
Ongoing |
NED (4 mo pS) |
- |
- |
Masserot #2 (2008)64
|
16.9 |
M |
NA |
Yes (11.2) |
Oral cavity (tongue) |
T2N+M0 |
22 Gy total |
NA |
Yes |
DOD (5.5 mo pD) |
- |
- |
Bremer #2 (2003)49
|
32 |
M |
NA |
No |
Pharynx (lateral and posterior oropharyngeal wall) |
T4cN2M0 |
8 Gy total (100 cGy x5 fractions, 150 cGy x2 fractions) |
Thrombocytopenia (grade 5) |
Yes (terminated) |
DOD (NA) |
- |
- |
Kozhevnikov 1986118
|
14 |
M |
NA |
No |
Oral cavity (gingiva) |
T3N0M0 |
80 Gy total |
Local bleeding |
NA |
DOD (6 mo pRT) |
- |
- |
Esparza 196695
|
26 |
F |
NA |
No |
Esophagus (middle) |
NA |
Dose NA |
NA |
NA |
DOD (4 mo pRT) |
- |
- |