Table 2.
Hematological parameters of the 4 groups of patients according to their rheumatoid arthritis disease activity.
| Characteristic | Total | Patients with disease remission | Patients with low disease activity | Patients with moderate disease activity | Patients with high disease activity | P valuea |
|---|---|---|---|---|---|---|
| Number of patients | 325 | 105 | 68 | 121 | 31 | |
| Hb (g/dL) | 11.9 (11.0–12.7) | 12.4 (11.5–13.1) | 12.1 (11.4–12.6) | 11.5 (10.7–12.2) | 10.8 (9.8–11.8) | <0.001 |
| RDW (%) | 14.9 (14.1–16.5) | 14.8 (14.0–16.2) | 14.6 (13.8–15.3) | 15.2 (14.3–16.6) | 16.5 (14.5–17.3) | 0.001 |
| WBC count (cells/μL) | 7400 (5700–9095) | 6800 (5500–8450) | 6900 (5625–8600) | 7900 (5850–9400) | 8500 (6400–10100) | 0.013 |
| WBC differential (%) | ||||||
| Neutrophil | 61.1 (53.9–68.4) | 58.3 (51.2–64.0) | 60.2 (52.2–68.0) | 63.4 (55.9–70.1) | 66.7 (60.2–73.8) | <0.001 |
| Lymphocyte | 28.0 (20.8–33.6) | 31.2 (24.3–36.0) | 28.9 (22.1–34.9) | 27.0 (20.1–33.0) | 23.0 (18.0–30.4) | 0.002 |
| Eosinophil | 2.0 (1.0–3.2) | 2.0 (1.3–3.4) | 2.0 (0.9–3.4) | 1.6 (0.9–3.5) | 1.9 (0.7–2.7) | 0.221 |
| Monocyte | 7.3 (5.9–9.2) | 7.9 (6.1–9.7) | 7.3 (5.7–9.2) | 7.2 (6.0–8.6) | 7.3 (5.4–9.0) | 0.189 |
| Basophil | 0.5 (0.2–0.7) | 0.5 (0.2–0.8) | 0.4 (0.2–0.6) | 0.5 (0.3–0.7) | 0.4 (0.1–0.6) | 0.131 |
| NLR | 2.2 (1.6–3.2) | 1.9 (1.4–2.6) | 1.5 (2.1–3.1) | 2.3 (1.7–3.5) | 3.0 (1.9–4.0) | 0.001 |
| Platelet count (103/μL) | 286 (241–332) | 268 (227–306) | 269 (229–305) | 311 (249–360) | 339 (280–429) | <0.001 |
| PLR | 10.8 (7.4–15.0) | 9.2 (6.4–12.5) | 10.2 (7.4–13.4) | 11.4 (8.2–16.7) | 15.6 (10.9–19.6) | <0.001 |
| MPV (fL) | 8.0 (7.3–8.8) | 8.3 (7.6–9.2) | 8.0 (7.2–8.6) | 8.0 (7.4–8.6) | 7.5 (7.1–8.6) | 0.022 |
Data are expressed as the median (IQR).
Hb, hemoglobin; IQR, interquartile range; MPV, mean platelet volume; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; RDW, red blood cell distribution width; WBC, white blood cell.
a
Kruskal-Wallis test.