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. 2016 Apr 29;2016(4):CD001750. doi: 10.1002/14651858.CD001750.pub4

Ferrero 2010.

Methods Randomised controlled trial, single centre
Participants 144 women
Inclusion criteria: no specific details but included women who had had moderate or severe OHSS or who had been at risk of OHSS during their first IVF/ICSI cycle with a mid‐luteal long agonist protocol
Exclusion criteria: no details
Setting and timing: Italy; no details of timing
Baseline characteristics: not stated
Interventions Antagonist ‐ cetrorelix 0.25 mg/day starting on day 3 of the menstrual cycle
Agonist ‐ triptorelin 0.1 mg/day starting on day 21 of the menstrual cycle
Ovarian stimulation was achieved with rFSH initiated on day 3 of the cycle at a maximum dose of 150 IU and dose adjusted depending on ovarian response
Luteal phase support ‐ with micronised progesterone vaginal gel (no other details)
Follow‐up ‐ followed‐up to live birth
Outcomes Live birth, clinical pregnancy, cancellation rate, oocytes retrieved
Notes As no denominators for groups are given, the data cannot be included in a meta‐analysis
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No details
Allocation concealment (selection bias) Unclear risk No details
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Open label but blinding unlikely to effect fertility outcome. No details of blinding of outcome assessors
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Although the abstract states that there were 144 women randomised, there are no other denominators to indicate how many women were allocated to each group. No details on withdrawals or losses to follow‐up
Selective reporting (reporting bias) Unclear risk Conference abstract only. Outcomes are not pre‐specified. OHSS not reported
Other bias Unclear risk Conference abstract only. Groups were reported as being similar at baseline