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. 2021 Oct;73(4):298–487. doi: 10.1124/pharmrev.120.000131

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Fig. 11 — Gating modulation of GluA1 and GluA1/GluA2 AMPA receptors by auxiliary subunits. (A) Channel conductance (γ_MEAN), (B) deactivation time constant (Tau_DEACTIVATE), (C) desensitization time constant (Tau_DESENS), and (D) ratio of amplitudes of steady state (I_SS) over peak currents (I_PEAK) are depicted by the location of the colored balloon that represents various auxiliary subunits in complex with the indicated receptor. The upper number line represents effects on the homomeric GluA1 (A1), whereas the lower number line represents effects on the heteromeric GluA1/2 (A1/A2). The white balloons indicate values for AMPA receptors without any auxiliary subunits. Values are from Table 2 and associated references. GL, GSG1L; CN, CNIH; CK, CKAMP; SD, SynDIG4. TARP subtypes are indicated as γ-2, γ-3, γ-4, γ-5 and γ-8.