Table 1.
positive control group (0.7% tetracycline gel application) | negative control group (mucoadhesive patch application) | experimental group (mucoadhesive patch loaded mangosteen peel extract application) | p | |
---|---|---|---|---|
3 days | 4.00 ± 1.00a | 5.33 ± 1.154 | 7.33 ± 1.54a | 0.046 |
5 days | 5.67 ± 1.15b | 7.67 ± 0.58 | 9.00 ± 1.00b | 0.046 |
7 days | 7.33 ± 1.80c | 9.67 ± 0.58 | 11.67 ± 2.08c | 0.044 |
a,b,c showed significant different with Mann–Whitney test.