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The number of osteoclasts.
| positive control group (0.7% tetracycline gel application) | negative control group (mucoadhesive patch application) | experimental group (mucoadhesive patch loaded mangosteen peel extract application) | p | |
|---|---|---|---|---|
| 3 days | 7.67 ± 0.58a | 6.57 ± 0.58 | 5.33 ± 0.58a | 0.043 |
| 5 days | 6.67 ± 0.58b | 5.33 ± 0.58 | 4.33 ± 1.15b | 0.043 |
| 7 days | 5.00 ± 1.00 | 4.33 ± 1.15 | 3.00 ± 1.00 | >0.05 |
a,b,c showed significant different with Mann–Whitney test.
