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. 2021 Nov 27;21:297. doi: 10.1186/s12871-021-01517-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — S100B was a target of miR-1182. A The relationship between miR-1182 and S100B was predicted by Targetscan. B and C The relationship between miR-1182 and S100B was validated by dual-luciferase reporter assay. D and E The relationship between miR-1182 and S100B was validated by RIP assay. F The expression of S100B in tumor tissues and normal tissues was checked by qPCR. G The correlation between S100B expression and miR-1182 expression in tumor tissues. H The expression of S100B in tumor tissues was detected by western blot. I The expression of S100B in IOSE-80, A2780 and SK-OV-3 cells was detected by western blot. J The efficiency of miR-1182 mimic and inhibitor was checked by qPCR. K The effects of miR-1182 enrichment or inhibition on S100B protein level were determined by western blot. ***P < 0.001