Table 3.

Recommendations for chemoprophylaxis in recent guidelines for patients with spontaneous ICH

Years	Organization	LMWH	UFH	Timing	Grade
2012	ACCP [26]	√	√	2–4 days	Weak recommendation, low-quality evidence
2014	ESO [27]	Not mentioned	Not mentioned	Not mentioned	Weak recommendation, low-quality evidence
2015	AHA/ASA [28]	√	√	Not mentioned	Weak recommendation, moderate-quality evidence
2016	NCS [29]	√	√	Within 48 h	Weak recommendation, low-quality evidence
2020	HSFC [31]	√	Not mentioned	After 48 h	Moderate-quality evidence

ACCP the American College of Chest Physicians; ESO European Stroke Organization; AHS/ASA the American Heart Association/American Stroke Association; NCS the Neurocritical Care Society; HSFC Heart and Stroke Foundation of Canada; UFH unfractionated heparin; LMWH low molecular weight heparin

√ recommended, × not recommended