Table 1.

Gene set enrichment analysis of METTL1

Gene set names	NOM p-val	FDR q-val
KEGG gene set
KEGG_CELL_CYCLE	1.61E−08	0.000000465
KEGG_P53_SIGNALING_PATHWAY	0.000027	0.000348425
KEGG_DNA_REPLICATION	0.0001745	0.001727684
KEGG_MAPK_SIGNALING_PATHWAY	0.0035289	0.020070548
HALLMARK gene set
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1E−10	4.05E−09
HALLMARK_G2M_CHECKPOINT	1E−10	4.05E−09
HALLMARK_INTERFERON_GAMMA_RESPONSE	1E−10	4.05E−09
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.0000015	0.000028
HALLMARK_KRAS_SIGNALING_UP	0.0031269	0.018333216
HALLMARK_IL2_STAT5_SIGNALING	0.0063964	0.031755704

Gene sets with NOM p-val and FDR q-value < 0.05 are considered as significant