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. Author manuscript; available in PMC: 2021 Nov 27.
Published in final edited form as: Cancer Gene Ther. 2020 Jan 20;27(9):625–633. doi: 10.1038/s41417-020-0160-4

Table 1.

Described m6A Member Machinery in Cancer

Component m6A role Role Cancer Studied References
FTO Eraser Oncogenic AML, GBM [48, 52]
ALKBH5 Eraser Oncogenic GBM, Breast, Pancreas [53, 66, 75]
METTL3 Writer Oncogenic, Tumor Suppressor AML, GBM, HCC, Pancreas, Breast [52, 67, 74, 77]
METTL14 Writer Tumor Suppressor GBM, HCC, Endometrial [36, 52, 73]
IGF3BP1/2/3 Writer Oncogenic GBM [22]
YTHDF1 Reader Oncogenic Colorectal Cancer, Melanoma [32]