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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Hepatology. 2021 Mar 16;73(5):1701–1716. doi: 10.1002/hep.31517

Figure 1. HSD17B13 is expressed in normal hepatocytes.

Figure 1.

(A) Gene expression of HSD17B13 in 53 healthy and 33 carcinoma tissues from the GTEx and TCGA databases. Cancer tissues are shown in red and normal tissues are shown in green. Data are sorted by median expression. (B) Tissue distribution of Hsd17b13 in mice. Gene expression of Hsd17b13 was determined in the liver, epididymal fat, inguinal fat, muscle, duodenum, jejunum, ileum, pancrase, kidney, testis, and heart tissues of 20 weeks old C57BL/6 mice by qPCR (n=6, Mean±SEM). (C) HSD17B13 is restrictively expressed within the hepatocyte cluster in human liver determined by single cell sequencing (http://human-liver-cell-atlas.ie-freiburg.mpg.de). (D) Single cell transcriptome data (https://tabula-muris.ds.czbiohub.org) showing the top 12 mouse cell types from 20 organs according to expression level of Hsd17b13, sorted by mean value.