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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Toxicol In Vitro. 2021 Aug 17;77:105234. doi: 10.1016/j.tiv.2021.105234

Figure 4: EpiDerm™ Exposed to Lab Made Refill Fluids for 4 hrs.

Figure 4:

(A-D) EpiDerm™ exposed for 4 hrs. to PG/ethyl maltol (PG EM) using three protocols (1 = 30 μL, 2 = 30 μL + 30 μL, and 3 = 60 μL). (A) MTT assay, (B) LDH assay, (C) IL-1α secretion, (D) secretion of MMP-9. (E-G) EpiDerm™ exposed to lab made refill fluids with protocol 2 for 4 hrs. total. (E) LDH assay, (F) secretion of IL-1α, and (G) secretion of MMP-9. Each bar is the mean ± standard error of the mean for three independent experiments. * = p < 0.05; ** = p < 0.01.