Table 2.

Relative abundance of multicopy elements IS6110 and IS1081 in urine cfDNA

Sample ID	TB status	cfDNA status (IS6110 qPCR)	IS6110 fold over-representationa	IS1081 fold over-representationa
01	Positive	Positive	0	0
02	Positive	Positive	0	0
03	Positive	Positive	17.0	2.52
04	Positive	Positive	1.27	0
05	Positive	Positive	3.30	6.78
06	Positive	Positive	3.68	3.62
07	Positive	Positive	17.1	8.48
08	Positive	Positive	6.34	1.72
09	Positive	Positive	0	0
10	Positive	Negative	0	0
11	Negative	Negative	0	0
12	Negative	Negative	0	0

cfDNA, cell-free DNA; IQR, interquartile range; MTB, Mycobacterium tuberculosis.

^aMeasured as the average sequencing depth in the target region normalized to the average sequencing depth across the remainder of the MTB genome.