Skip to main content
. 2021 Nov 27;21:268. doi: 10.1186/s12874-021-01463-y

Table 1.

Hierarchy of evidence

Level ES document
(used for effect size estimation)
Included studies
1 A review of reviews of RCTs Overview; umbrella review; meta-review; (systematic) review of (systematic) reviews
2 A systematic review of RCTs from Cochrane collaboration Systematic review, meta-analysis and their combination
3 Other systematic review of RCTs Systematic review, meta-analysis and their combination
4 RCTs in which case they were considered equally relevant ES documents from which we calculated the combined effect size RCTs
5 Non-randomised controlled studies in cases were true randomisation was not feasible or ethical Non-randomised controlled studies