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Putamen connectivity with the left lateral orbitofrontal cortex (OFC) was correlated positively with both impulsivity (left) and duration of ketamine use (right). (a) Voxels shown in yellow represent those that overlap between the two regressions. (b) and (c) show the results of significant mediation of the relationship of BIS-11 score and months of ketamine use, bidirectionally, by the connectivity of the overlapping voxels.
