3. Commonly used medications in diabetes mellitus (type 1 and type 2) for the management of hyperglycaemia.
Class/Drug | Expected decrease in HbA1c |
ORAL ANTIDIABETIC THERAPY | |
Metformin | 1% to 2% |
Sulfonylureas
|
1% to 2% |
DPP‐4‐inhibitors
|
0.5% to 0.8% |
Acarbose | 0.5% to 0.8% |
Thiazolidinedione (glitazones)
|
0.5% to 1.4% |
PARENTERAL THERAPY | |
GLP‐analogues
|
0.5% to 1.0% |
Insulin | 1.5% to 3.5% |
Insulin | Generic name |
Very‐short‐acting (rapid) | Aspart Glulisine Lispro |
Short‐acting | Neutral |
Intermediate‐acting | Isophane (protamine suspension) |
Long‐acting | Determir Glargine |
Biphasic | Neutral/isophane Lispro/lispro protamine Aspart/aspart protamine |
Methods of insulin delivery | |
|