Table 1.
Patients’ Characteristics.
| Variable | PWS (n=18) | |
|---|---|---|
| Age, years | 28±9 | |
| Male/Female | 11/7 | |
| BMI, kg/m2 | 45.1±11.6 | |
| Hypertension, % | 78 | |
| Systolic blood pressure, mmHg | 135±13 | |
| Diastolic blood pressure, mmHg | 77±9 | |
| Diabetes mellitus, % | 82 | |
| HbA1C, % | 9.0±2.8 | |
| Dyslipidemia | 94 | |
| TG, mg/dL | 155 (107-263) | |
| HDL mg/dL | 46±7 | |
| LDL, mg/dL | 125±27 | |
| CKD, % | 0 | |
| TSH, μU/mL | 2.4±1.4 | |
| WBC, μL | 9,150 (8,000-12,000) | |
| hs-CRP, mg/dL | 1.007±0.538 | |
| BNP, pg/mL | 17.4±19.8 | |
| Troponin T, ng/mL | 0.007±0.009 | |
| Medications | ||
| ARB, n (%) | 10 (58) | |
| Calcium channel blocker, n (%) | 10 (58) | |
| Diuretics, n (%) | 8 (42) | |
| Statin, n (%) | 12 (67) | |
| Metformin, n (%) | 11 (61) | |
| SGLT-2 inhibitor, n (%) | 1 (6) | |
| α-GI, n (%) | 4 (22) | |
| DPP-4 inhibitor, n (%) | 9 (50) | |
| Insulin, n (%) | 8 (44) | |
| Sex hormones, n (%) | 3 (17) |
Values are n, mean±SD or median (interquartile range).
PWS: Prader-Willi syndrome, BMI: body mass index, HbA1C: hemoglobin A1C, TG: triglyceride, HDL: high density lipoprotein, LDL: low density lipoprotein, CKD: chronic kidney disease, TSH: thyroxine-stimulating hormone, WBC: white blood cell, hs-CRP: high-sensitive C-reactive Protein, BNP: brain natriuretic peptide, ARB: angiotensin II receptor blocker, SGLT-2 inhibitor: sodium-glucose cotransporter-2 inhibitor, α-GI: α-glucosidase inhibitor, DPP-4 inhibitor: dipeptidyl peptidase-4 inhibitor