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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Periodontal Res. 2021 Aug 9;56(6):1046–1057. doi: 10.1111/jre.12918

FIGURE 1.

FIGURE 1

PKP2 expression in gingiva biopsies. (A) PKP2 expression was primarily localized to gingival epithelium in gingival biopsies. Scale bar is 130 μm. Periodontitis biopsies displayed disrupted epithelium, prominent rete pegs, and more immune cell infiltrates (white arrows). PKP2 was detected in endothelial cells and fibroblast at a moderate level (lower right panel). (B) Periodontitis biopsies had about twofold less PKP2 mRNA expression than those with healthy gingival biopsies. (C) KRT5 mRNA expression was not significantly different among those three groups. (D) The fold change ratio of PKP2/KRT5 remained significantly less in periodontitis biopsies than in healthy gingiva and experimental gingivitis biopsies. * indicates p < .05; ** indicates p < .01